On October 14, 2014, the 4th FUSCC-CRIKU Joint Symposium on Tumor Biology was convened at FUSCC. Prof. Masanobu Oshima and Prof. YE Dingwei addressed the meeting, and seven researchers representing both sides made presentations on the pioneering researches on leukemia stem cells and tumor metastasis and therapeutic resistance, MicroRNAs and resistance mechanism, and therapeutic target and tumor microenvironment in lung cancer.