FIND DOCTORS
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Name: Yang,Wentao
Department: PATHOLOGY
Title:ProfessorEducation & Professional Experience Professor, Department of Pathology, Fudan University, Cancer Hospital, Shanghai, China.05、2009-present
Associate Professor, Department of Pathology, Fudan University, Cancer Hospital, Shanghai, China.11/2002-04/2009
Post-doctoral Fellow, Department of Surgical Oncology, M. D. Anderson Cancer Center, Houston, Texas, U. S. A. 09/2000-02/2002
Attending Doctor, Department of Pathology, Fudan University, Cancer Hospital, Shanghai, China.07/1999-10/2002
Visiting Fellow in Department of Pathology, Frankfurt University Medical School, Frankfurt, Germnay. 09/1998-02/1999
Shanghai Medical University, Shanghai, P. R. China. Ph.D., 09/1996-07/1999, Oncology
Resident, Department of Pathology, Fudan University, Cancer Hospital, Shanghai, China.07/1996-07/1999
Shanghai Medical University, Shanghai, P. R. China. M.A., 09/1993-07/1996, Oncology
Shanghai Medical University, Shanghai, P. R. China. M.D., 09/1988-07/1993, Medicine
Shanghai Kong Jiang High School, 09/1985-07/1988
Research 1). Principal Investigator, National Natural Science Foundation Project, NSFC, RMB180,000 (2002)
2) Principal Investigator,Principal Investigator, National Natural Science Foundation Project,NSFC, RMB190,000 (2004)
3) Principal Investigator,Program for New Century Excellent Talents in University, RMB500,000（2005）
4) Principal Investigator,Shanghai Rising-star Program, RMB100,000（2005）
5） Principal Investigator, Shanghai Natural Science Project, RMB 100,000 (2010)Publication 1. Yu L, Yang W (Corresponding Author). Centrally necrotizing carcinoma of the breast: clinicopathological analysis of 33 cases indicating its basal-like phenotype and poor prognosis. Histopathology 2010 ;57(2):193-201
2. Yu L, Yang W (Corresponding Author). Pulmonary blastoma metastatic to the ovary. Int J Gynecol Pathol 2009;28(1):59-62
3.Shui R, Yang W (Corresponding Author). Invasive breast carcinoma arising in microglandular adenosis: a case report and review of the literature. Breast J 2009;15(6):653-656
4. Yang W, Klos K, Zhou X, Yao J, Yang Y, Smith TL, Shi D, Yu D. ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression. Cancer 2003;98:1123-1130
5. Yang W, Klos K, Yang Y, Smith TL, Shi D, Yu D. ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinoma. Cancer 2002; 94(11): 2855-2861
6. Lee S, Yang W, Lan KH, Sellappan S, Klos K, Hortobagyi G, Hung MC, Yu D. Enhanced Sensitization to Taxol-Induced Apoptosis by Herceptin Pretreatment in ErbB2-Overexpressing Breast Cancer Cells. Cancer Res, 2002; 62: 5703-5710
7. Brauninger A, Yang W, Wacker HH, Rajewsky K, Kúppers R, Hansmann ML. B-cell development in progressively transformed germinal centers: similarities and differences compared with classical germinal centers and lymphocyte-predominant Hodgkin disease. Blood 2001; 97(3): 714-719
8. Klos KS, Wyszomierski SL, Sun M, Tan M, Zhou X, Li P, Yang W, Yin G, HIttelman WN, Yu D. ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells. Cancer Res 2006;66(4):2028-37
9.Zhou X, Tan M, Stone Hawthorne V, Klos KS, Lan KH, Yang Y, Yang W, Smith TL, Shi D, Yu D. Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res 2004;10(20):6779-6788
10.Sellappan S, Grijalva R, Zhou X, Yang W, Eli MB, Mills GB, Yu D. Lineage infidelity of MDA-MB-435 cells: expression of melanocyte proteins in a breast cancer cell line. Cancer Res 2004;64(10):3479-3485
11.Klos KS, Zhou X, Lee S, Zhang L, Yang W, Nagata Y, Yu D. Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone. Cancer 2003;98(7):1377-1385
12. Yu L, Yang W(Corresponding Author), Cai X, et al. Clinicopathologic study of centrally necrotizing carcinoma of breast. Chinese J Pathol 2009;38(10):657-662
13. Yang W, Li D. The pathology diagnosis of breast mucinous lesions. Chinese J Pathol 2009;38(9):633-636
14.Li D, Yang W(Corresponding Author). The problems in the pathology diagnosis of benign breast lesions. Chinese J Pratical Surg 2009;29(3):199-202
15. Yu L, Yang W(Corresponding Author). Uterine Mass. Chinese J Pathol 2008;37(12):847-848
16.Yang W，Yu L，Lu H，et al. Clinicopathologic study of intracystic papillary carcinoma of the breast. Chinese J Pathol 2008;37(4):234-237
17.Zhang G，Yang W (Corresponding Author),Zhou X, et al. Study of the correlation between HER-2 gene and lymphangiogenesis and their prognostic significance in human breast cancer. National Medical Journal of China. 2007;87(3):155-160
18. Zhang G，Zeng Y，Yang W (Corresponding Author). Study of mRNA expression of vascular endothelial growth factor -(A,C,D) genes and its effect on prognosis of breast cancer. Chinese J Pathol 2006;35(8):473-477
19. Yang W, Lu H，Zhang T, et al. Wolffian adnexal tumor:a pathological study of 3 cases. Chinese Journal of Clinical and Experimental Pathology 2006;22(6):257-260
20. Yang W，Xu Y, Zhang T. Clinicopathologic study of breast cancer with features of endocrine ductal carcinoma-in-situ. Chinese J Pathol 2006;35(10):594-597
21. Chen X，Yang W，Wu X，et al. Primary ovarian small cell carcinoma of the pulmonary type:three cases report and review of the literature. Chinese Journal of Obstetrics and Gynecology, 2006;41(7):481-483
22. Gao H, Yang W, Wang J. Superficial cervicovaginal myofibroblastoma:case report with a review of the literature. Chinese Journal of Clinical and Experimental Pathology 2005;21(4):414-418
23. Zeng Y, Yang W, Zhang G, et al . Study of HOXA5 gene expression in breast carcinoma. Chinese J Pathol 2005;34(9): 569-574
24.Yang W，Zhang T，Shen M，et al. Adenoid cystic carcinoma of the breast: report of four cases and review of the literature. Chinese Journal of Clinical and Experimental Pathology 2005;21(1):10-13
25. Liu X, Yang W，Zhou X, et al. Preliminary analysis of mutations in exon 5 of IκBα gene in Hodgkin lymphoma. Chinese J Pathol 2005;34(6):341-344
26.Shi J，Yang W(Corresponding Author)，Chen T，et al. Fibromatosis-like spindle cell carcinoma of the breast. Chinese Journal of Clinical and Experimental Pathology 2005;21(1):117-120
27. Chen T，Yang W，Zhu X，et al. Thirty base pair (30 bp) deletion in latent membrane protein 1 oncogene in lymphoepithelial carcinoma of salivary glands. Chinese J Pathol 2004; 33(3): 229-232
28. Chen T，Yang W，Zhu X，et al. 30-bp deletion in latent membrane protein 1 (LMP-1) oncogene in lymphoepithelial carcinoma of salivary glands. Chinese J Cancer Res 2004;16(3): 167-170
29. Yang W，Zhang T. Differential diagnosis of primary ovarian tumors. Chinese Journal of Diagnostic Pathology，2004;11(5):292-294
30. Min D，Zhou X，Yang W，et al. Study of mutations in 5′-noncoding region of BCL-6 gene in B-cell non-Hodgkin′s lymphomas. Chinese Journal of Pathology 2004 ;33(3):238-241
31. Shui R，Yang W，Sun M, et al. Detection of cyclin D1 protein expression and t (11;14) chromosomal translocation in paraffin-embedded tissues and its clinicopathologic significance for mantle cell lymphoma. Chinese Journal of Pathology 2003; 32(4): 337-341
32. Yang W, Xu L, Zhu X. Progressively transfromed germinal center. Chinese Journal of Pathology 2001;30(2):133-134
33.Yang W, Xu L. Techniques in isolating single-cell from tissue slides and its application. Chinese Journal of Diagnostic Pathology 2001; 8(2):124-125
34. Yang W, Xu L, Zhang T, et al. Single-cell DNA sequencing in the study of immunoglobulin gene rearrangement. Chinese Journal of Pathology 2001;30(2): 141-143
35. Yang W, Zhang T, Fan J, et al. The role of CA125 in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract. Chinese Journal of Obstetrics and Gynecology 2001;36(5):302-303
36. Zhu X, Yang W. Recent advances in the role of patholgy in breast cancer diagnosis and treatment. Chinese Journal of Pathology, 2000;29(3):165-167
37. Yang W, Xu L, Zhang T, et al. Telomerase activity and its significance in malignant lymphomas. China Oncology 2000;10(4):323-325
38. Yang W, Xu L. Preliminary Study of Single Cell Isolation and Single Cell PCR in Lymph Node Germinal Centers. Journal of Shanghai Medica(University) 2000;27(6): 460-463
39.Yang W, Zhang T, Shen M, et al. Metastatic ovarian carcinoma of gastric origin :a clinicopathological study of 43 cases. Chinese Journal of Diagnostic Pathology， 2000; 7(3): 170-3
40. Yang W. Recent advances in telomearse study of breast cancer. China Oncology 1999;9(4): 337-9
41. Yang W, Xu L, Zhang T, et al. Telomerase activity in breast carcinoma. Chinese Journal of Oncology 1999; 21(4):278-280
42.Yang W，Zhang T，Shen M, et al. Metastatic ovarian carcinoma of intestinal origin:a clinicopathological and immunohistochemical study. Chinese Journal of Diagnostic Pathology 1999;6(1):10-12
43. Yang W, Xu Liangzhong, Zhang Taiming, et al. Detection of telomerase activity in breast carcinoma. Chinese J Cancer Res 1998,10:235-238
44. Yang W，Xu L，Zhang T, et al. Epstein-Barr Virus Infection in Breast Ccancer. Journal of Shanghai Medica(University) 1998,25:175-177
45. Yang W，Zhang T，Shen M, et al. The role of cytokeratin 7 in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract. Chinese Journal of Pathology 1998,27:206-208
46. Zhang T，Yang W. The value of microvessel density in invasive breast carcinoma. China Oncolgy 1997,7:86-89
47. Xu L，Yang W. The criterion of immunohistochemistry results judgement. China Oncology 1996,6:229-231
